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Trifexis For Dogs: Uses, Dosage, & Side Effects

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Trifexis is a medication for dogs that kills fleas and prevents infestation, prevents heartworm, and treats and prevents many kinds of worm infestations.

Trifexis has had some controversy, as a few years ago, several dog parents reported that the medication caused or was a contributing factor in their dogs’ deaths. While there may have been a correlation between dog deaths and use of Trifexis, a causation couldn’t be proven, and Snopes.com rates the claim that Trifexis causes dog deaths as “undetermined.”

If these reports cause you concern, you must consult your veterinarian, do some research, and read reviews, or you should consider alternative treatment for fleas or worms. You can get Trifexis with your vet’s prescription from Chewy’s online pharmacy here.

Here’s what you should know about the uses, dosage, and side effects of Trifexis.

Uses Of Trifexis For Dogs

Yellow Labrador Retriever lying down scratching usings hind leg
(Picture Credit: Getty Images)

Trifexis is used to kill fleas and prevent further infestation in dogs. The manufacturer suggests that it starts to kill fleas within 30 minutes of being taken and eliminates all of them within four hours.

Trifexis is effective for 30 days of protection against infestation. It protects against heartworm and intestinal parasites, and it treats and controls adult hookworm, roundworm, and whipworm infections.

The manufacturer does warn that “Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention.”

Dosage Of Trifexis For Dogs

Veterinarian doctor writing prescription after cute white dog exam in clinic
(Picture Credit: Getty Images)

The usual dosage of Trifexis for dogs depends on weight. Each package has an indicator of what weight of dogs that it is suited for.

If you have a 15 pound dog, for example, you should stick to the Trifexis medication for 10 to 20 pound dogs.

Trifexis comes in a chewable, beef-flavored tablet that dogs should take once every 30 days to remain effective.

Side Effects Of Trifexis For Dogs

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(Picture Credit: Getty Images)

The most common side effect of Trifexis for dogs is vomiting, though there are several other side effects you should be aware of before you give the medication to your dog.

If side effects become concerning, then you should contact your veterinarian. They may wish to use an alternative form of treatment.

Here are some side effects of Trifexis observed in dogs:

  • Itching
  • Redness of ears or skin
  • Loss of appetite
  • Diarrhea
  • Lethargy

You should discuss any other medication your dog is taking with your veterinarian, as it can react badly with Trifexis.

Your vet should also be aware of any other medical conditions your dog has, especially epilepsy. Certain conditions may make it unsafe for your dog to take this medication. It may also not be right for pregnant dogs or very young puppies.

As with all medication, there is a risk of allergic reaction that could lead to anaphylaxis. If you see the signs of an allergic reaction, then you should contact your veterinarian immediately.

While there is no conclusive link between Trifexis and dogs’ deaths, you should ask your veterinarian if you’re concerned, read product reviews, and research the issue for yourself. There are alternative treatments available for fleas and worms, and sometimes it’s better to be safe than sorry.

Has your dog ever taken Trifexis? Did you find it effective? Then let us know in the comments below!

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